2020-07-20 11:31:45 浏览数:0
基本信息
姓名:于颖 性别:女
学位:博士 政治面貌:中共党员
籍贯:山东 荣成
硕/博导:硕士研究生导师 职称:副高级
邮箱:yuyingeng@163.com QQ: 405412167
教育背景
1. 2004-09至2008-07 山东农业大学 制药工程专业 学士;
2. 2008-09至2011-07 山东农业大学 预防兽医学专业 硕士;
3. 2012-09至2015-07 西北农林科技大学 预防兽医学专业 博士。
工作经历
1. 2015-07至2019-07 中国农业科学院哈尔滨兽医研究所 助理研究员
2. 2015-10至2019-06 中国农业科学院哈尔滨兽医研究所 博士后
3. 2019-08至今:必威BETWAY官网 教师
研究方向
主要从事猪繁殖与呼吸综合征(PRRS)及猪圆环病毒III型、支原体等免疫抑制性疾病的研究:
1. 在应用研究方面从事PRRSV、PCV3等疫苗的免疫保护性研究以及干扰素等生物制品的临床试验,对外开展动物疫病防控技术服务。在猪的病毒病和细菌病的抗原检测和抗体检测方面,具备成熟的检测体系和对外开展技术服务的软硬件条件。
2. 基础研究方面,主持或参加多项国家级、省部级项目,主要有国家自然科学基金面上和青年项目、国家重点研发计划、横向课题等围绕以上课题开展研究以第一作者发表SCI论文十余篇,正在申报多个生物诊疗制剂的国国际专利和国家发明专利。
主持课题情况
1. 国家自然科学基金青年基金“鸡毒支原体GroEL蛋白诱导DF-1细胞凋亡的分子机制”,31602084,20170101-20191231,直接经费20万元,课题主持。
2. 山东省自然科学基金面上项目“PRRSV 感染猪骨髓源树突状细胞诱导其凋亡的分子机制”,ZR2021MC008,2022-1至2024-12,10万元,课题主持。
3. 必威BETWAY官网高层次人才基金,1120019,HP-PRRSV感染PBMCs诱导其免疫异常的分子机制,10万元,课题主持。
4. 兽医生物技术国家重点实验室开放课题,SKLVBF202115,PRRSV感染诱导机体免疫异常的分子机制,8万元,课题主持。
发表论文
1. Yu Y, Zhang L, Chen Y, Li Y, Wang Z, Li G, Wang G*, Xin J*. GroEL protein (Heat shock protein 60) of Mycoplasma gallisepticum induces apoptosis in host cells by interacting with Annexin A2. Infect. Immun. 2019, 87:9. IF: 3.16
2. Yu Y*, Zhang Q, Cao Zhi, Tang Y, Xia D, Wang G*, Shan H*. Recent Advances in Porcine Reproductive and Respiratory Syndrome Virus NADC30-Like Research in China: Molecular Characterization, Pathogenicity, and Control. Frontiers in Microbiology. 2021, 12:0-791313. IF: 5.64
3. Wang G#, Yu Y#, Cai XH, Zhou E-M, Zimmerman JJ*. Effects of PRRSV infection on the porcine thymus. Trends Microbiol. DOI: 10.1016/j.tim.2019.10.009. IF: 17.079
4. Yu Y, Chen Y, Wang Y, Li Y, Zhang L, Xin J*. TLR2/MyD88/NF-kappaB signaling pathway regulates IL-1β production in DF-1cells exposed to Mycoplasma gallisepticum LAMPs. Microb Pathog. 2018.117: 225-231. 引用次数1 IF: 2.581
5. Wang G#, Yu Y#, He X, Wang M, Cai X, Zimmerman JJ*, Porcine reproductive and respiratory syndrome virus infection of bone marrow: Lesions and pathogenesis. Virus Res. 2019, 265: 20-29. ( #:共同第一作者) IF: 2.58
6. Tong J#, Yu Y#, Zheng L#, Zhang C, Tu Y, Liu Y, Wu J, Li H, Wang S, Jiang C, Zhou EM, Wang G*, Cai X*. Hypothalamus-pituitary-adrenal axis involves in anti-viral ability through regulation of immune response in piglets infected by highly pathogenic porcine reproductive and respiratory syndrome virus. BMC Vet Res. 2018, 14, 92. (#:共同第一作者) IF: 1.792
7. Wang G#, Yu Y#, Zhang C, Tu YB, Tong J, Liu YG, Chang YF, Jiang CG, Wang SJ, Zhou E-M*, Cai XH*. Immune responses to modified live virus vaccines developed from classical or highly pathogenic PRRSV following challenge with a highly pathogenic PRRSV strain. Dev Comp Immunol. 2016, 62: 1-7. (#:共同第一作者) 引用次数13 IF: 3.119
8. Wang G#, Yu Y#, Tu YB, Li YM, Tong J, Zhang C, Liu YG, Li AD, Jiang CG, Wang SJ, Tao Y, Cai XH*.Characterizing the thymic lesions in piglets infected with attenuated strains of highly pathogenic porcine reproductive and respiratory syndrome virus. Vet Immunol Immunopathol. 2015, 15(3-4): 258-61. (#:共同第一作者) 引用次数3 IF: 1.876
9. Wang G#, Yu Y#, Tu Y, Tong J, Liu Y, Zhang C, Chang Y, Wang S, Jiang C, Zhou EM*, Cai X*. Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Infection Induced Apoptosis and Autophagy in Thymi of Infected Piglets. PLoS One. 2015, 10, e0128292. (#:共同第一作者) 引用次数18 IF: 3.057
10. Yu Y, Wang G, Li Q, Du Y, Du T, Mu Y, Xiao S, Zhao Q, Wang C, Sun Yi, Xu X, Zhang G, Hsu WH, Cai X, Zhou E-M. Single-chain antiidiotypic antibody retains it specificity to porcine reproductive and respiratory syndrome virus GP5. Immunol Lett. 2015, 163(4): 8-13. IF: 2.483
11. Yu Y, Cai XH, Wang G, Kong N, Liu YG, Xiao YH, Zhang C, Mu Y, Xiao SQ, Zhao Q, Wang CB, Zhang GP, Hiscox JA, Zhou EM*. Anti-idiotypic antibodies reduce efficacy of the attenuated vaccine against highly pathogenic PRRSV challenge. BMC Vet Res. 2014, 10: 39.引用次数10 IF:1.792
12. Wang G, Li L, Yu Y, Tu YB, Tong J, Zhang C, Liu YG, Li YM , Han ZF, Jiang CG, Wang SJ, Zhou E-M, He XJ*, Cai XH*. Highly pathogenic porcine reproductive and respiratory syndrome virus infection and induction of apoptosis in bone marrow cells of infected piglets. J Gen Virol. 2016, 97: 1356-1361. 引用次数12 IF: 3.192
13. Wang G, Song TF, Yu Y, Liu YG, Shi WD, Wang SJ, Rong FL, Dong JG, Cai XH*, Zhou EM*. Immune Responses in Piglets Infected with Highly Pathogenic Porcine Reproductive and Respiratory Syndrome. Vet Immunol Immunopathol. 2011, 142(3-4):170-8. 引用次数53 IF: 2.076
编辑:许鹏举
责任编辑:和法华